Dr Darren Cook

Post Doctoral Senior Research in Medecine Assistant

Areas of interest

Wolbachia bacteria of filarial nematodes , Wolbachia as an anti-filarial drug target. The effect of anti-Wolbachia drugs on the development of infective filarial larvae.

Background

Darren Cook graduated from the University of Hull in 1999 with a B.Sc. in Biology and the following year graduated from the University of Manchester with an M.Sc. in Molecular Parasitology and Vector Biology. After 5 months voluntary work examining transmission of toxoplasmosis at Salford University, he joined Dr Sylvie Ducki as a laboratory technician as part of an international collaboration to discover new drugs for the treatment of cancer. Darren joined the Liverpool School of Tropical Medicine in 2005 working on novel camelid antivenoms for the treatment of snakebite under Dr Rob Harrison’s supervision and obtained his Ph.D. in 2010. In April 2010 Darren joined Prof. Mark Taylor’s group in the Filariasis Research in Medecine Laboratory as a post-doctoral research assistant.

Selected publications

  • Selected Publications

    Cook DA, Samarasekara CL, Wagstaff SC, Kinne J, Wernery U and Harrison RA (2010). Analysis of camelid IgG for antivenom development: Immunoreactivity and preclinical neutralisation of venom-induced pathology by IgG subclasses, and the effect of heat treatment. Toxicon 56: 596-603.

    Cook DA, Owen T, Wagstaff SC, Kinne J, Wernery U and Harrison RA (2010). Analysis of camelid antibodies for antivenom development: Neutralisation of venom-induced pathology. Toxicon 56: 373-380.

    Cook DA, Owen T, Wagstaff SC, Kinne J, Wernery U and Harrison RA (2010). Analysis of camelid IgG for antivenom development: Serological responses of venom-immunised camels to prepare either monospecific or polyspecific antivenoms for West Africa. Toxicon 56: 363-372.

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