Professor Graham Devereux

Professor Respiratory Medicine

Graham went to medical school in Cambridge and Oxford. He then trained in Respiratory and General Medicine in Newcastle, Nottingham and Aberdeen. He undertook two periods of research during this training and has an MD in asthma epidemiology a PhD in neonatal immunology. In 2000 he was appointed as a Consultant in Respiratory and General Medicine in Aberdeen, he has developed clinical sub-speciality interests in airways disease (asthma, COPD, cystic fibrosis and bronchiectasis). In 2005 he accepted a post as a Clinical Senior Lecturer at the University of Aberdeen, and in 2008 he was promoted to Professor of Respiratory Medicine. He is an Honorary Consultant in Respiratory Medicine at Aintree University Hospitals NHS Foundation Trust.

Research in Medecine

Graham has established research interest in the early life influences on the life course of respiratory disease. He has identified associations between childhood asthma and maternal diet during pregnancy, fetal growth patterns and parental occupation. Translational aspects of this work have identified associations between maternal exposures during pregnancy and cord blood immune responses and neonatal airway epithelial cell responses.
In conjunction with Novabiotics Graham has been investigating the possibility of repurposing cysteamine for use in cystic fibrosis during acute exacerbations and as chronic maintenance therapy.

Most recently he has been Co-Chief investigator for the NIHR-HTA funded trial of low dose theophylline in COPD (TWICS) and he is Co-Chief investigator for the NIHR-HTA funded trial of Bisoprolol in COPD (BICS).

Graham is expert advisor to Ministry of Defence Research in Medecine Ethics Committee.

 

Selected publications

  • Devereux G. The increase in the prevalence of asthma and allergy: food for thought. Nature Rev Immunol, 2006; 6: 869-74.

    Devereux G, Turner SW, Craig LCA, McNeill G, Martindale S, Harbour PJ, Helms PJ, Seaton A. Reduced maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med 2006: 174; 499-507.
    Devereux G, Litonjua AA, Turner SW, Craig LCA, McNeill G, Martindale S, Helms PJ, Seaton A, Weiss ST. Maternal vitamin D intake during pregnancy and early childhood wheeze. Am J Clin Nutrition 2007; 85:853-9.
    Turner SW, Campbell D, Smith N, Craig LCA, McNeill G, Forbes SH, Harbour PJ, Seaton A, Helms PJ, Devereux GS. Associations between fetal size, maternal alpha-tocopherol and childhood asthma. Thorax 2010; 65: 391-7.
    Nurmatov U, Devereux G, Sheikh A. Nutrients and foods for the primary prevention of asthma and allergy: systematic review and meta-analysis. J Allergy Clin Immunol 2011; 127: 724-33.
    Kurmi OP, Devereux GS, Smith WCS, Semple S, Steiner MFC, Simkhada P, Lam KH, Ayres JG. Reduced lung function due to biomass smoke exposure in young adults in rural Nepal. Eur Respir J. 2013; 41:25-30
    Allan KM, Prabhu N, Craig LCA, McNeill G, Kirby B, McLay J, Helms PJ, Ayres JG, Seaton A, Turner SW, Devereux G. Maternal intakes of vitamin D and E during pregnancy are associated with asthma in children. Eur Resp J 2015; 45:1027-1036.
    Tagiyeva N, Devereux G, Fielding S, Turner S, Douglas G. Outcomes of childhood asthma and wheezy bronchitis - a 50-year cohort study. Am J Respir Crit Care Med 2016; 2016 193:23-30.
    McKeever T, Mortimer K, Wilson A, Walker S, Brightling C, Skeggs A, Pavord I, Price D, Duley L, Thomas M, Bradshaw L, Higgins B, Haydock R, Mitchell E, Devereux G, Harrison T. Quadrupling Inhaled Glucocorticoid Dose To Abort Asthma Exacerbations. New England Journal of Medicine. 2018; 378:902-910.

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