Valeriu Crudu

Principal Investigator: HIV-TB in One

Head of Microbiology and Morphology Laboratory,
Phthisiopneumology Institute,
"Chiril Draganiuc", Chisinau, Moldova

Dr. Valeriu Crudu is currently working as Associate professor, Head of Microbiology & Morphology of Laboratory of Phthisiopneumology Institute from Moldova. WHO temporary adviser in infection controls in TB and laboratory assessments. More than 30 years of experience in laboratory assessment, laboratory network, diagnostic guidelines, infectious disease surveillance; large scientifically experience in the field of M.tuberculosis research. Authored or co-authored of 180 publications. Leading authority on Infection Control and multi drug-resistant TB in Moldova; member of the European Society of Clinical Microbiology and Infectious Diseases, European Respiratory Society, International Union Against Tuberculosis and Lung Disease, TB PANNET European. Extensive collaborations with scientific partners from Germany, US, France, Romania, United Kingdom, Leetonia, Russia, Ukraine and other countries. The most important area of interest are: genotyping of Mycobacterium, new rapid method for TB diagnostic, molecular genetics methods for drug sensitivity testing, management of drug resistance TB, nosocomial transmission of TB, new therapeutic compounds with anti-TB activity.

Research in Medecine Interest
Dr. Valeriu Crudu Research in Medecine Interests includes Genotyping of Mycobacterium, new rapid method for TB diagnostic, molecular genetics methods for drug sensitivity testing, management of drug resistance TB, nosocomial transmission of TB, new therapeutic compounds with anti-TB activity.

Selected Publications

Chesov D, Ciobanu N, Large C, Schon T, Heychendorf J, Crudu V.Lack of evidence of isoniazid efficacy for the treatment of MDR/XDR-TB in the presence of the katG 315T mutation. Eur Respir J. 2017 Oct 12;50(4). pii: 1701752. doi: 10.1183/13993003.01752-2017. IF: 10.56

Chesov D, Ciobanu N, Lange C, Heychendorf J, Crudu V. High-dose isoniazid in the shorter-course multidrug-resistant tuberculosis regimen in the Republic of Moldova. Eur Respir J. 2017 Oct 12;50(4). pii: 1701340. doi: 10.1183/13993003.01340-2017. IF: 10.56

Dedicoat MJ, Günter G, Crudu V, Lange C; et.al. Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure. Am J Respir Crit Care Med. 2017 Nov 1;196(9):1222-1224. doi: 10.1164/rccm.201612-2585LE. IF 13.204

Valeriu Crudu, Matthias Merker, Christoph Lange, Ecaterina Noroc, Elena Romancenco, Dumitru Chesov, Gunar Günther, Stefan Niemann. Nosocomial transmission of multidrug-resistant tuberculosis. JTLD-04-15-0327 IF 2.7

Matthias Merker, Maxime Barbier, Helen Cox, Jean-Philippe Rasigade, Silke Feuerriege, Thomas A. Kohl, Egor Shitikov, Kadri Toit, Roland Diel, Sonia Borrell, Sebastien Gagneux, Vladyslav Nikolayevskyy, Valeriu Crudu, Ulrich Nübel, Philip Supply, Thierry Wirth, Stefan Niemann. Historic emergence and recent expansion of multidrug-resistant tuberculosis in Eurasia. NEJM, 2016. IF: 59.56

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